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Tests for Cellular Immunity (DTH)
Inpatient and out patient allergy and Immunology consultations
A tiny amount of protein is injected into the skin. In 24 hours or so, a hard, red nodule develops at the site of the injection. This nodule is densely packed with lymphocytes and macrophages. The response to antigen is called "delayed" because of the time it takes to occur (in contrast to the "immediate" responses characteristic of many antibody-mediated sensitivities like an allergic response to a bee sting). DTH is a cell-mediated response. The T cells responsible for DTH are members of the CD4+ subset. |
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